Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFC0190)
HIF Name	Helios RORt+CTLA4hi ICOShi IL10+FOXP3+CD4+ regulatory T cells
HIF Synonym(s)	Helios RORt+ CTLA4hi ICOShi IL10+ FOXP3+ CD4+ Tregulatory cells, Helios RORt+CTLA4hi ICOShi IL10+FOXP3+CD4+ Tregulatory cells
HIF Classification	T cells (TCs)
Description	Helios RORt+ CTLA4hi ICOShi IL10+ FOXP3+ CD4+ Tregulatory cells is a type of the immune cells.	[1]

Microbe Species (MIC) Regulated by This HIF
Clostridia bacterium (firmicutes)		MIC01982
Description	Clostridia clusters VI is related to the differentiation, proliferation and recruitment of HeliosRORt+CTLA4hiICOShiIL10+FOXP3+ CD4+ Treg cells in the colon.		[2]

References
1	A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.PLoS One. 2016 Mar 3;11(3):e0150606. doi: 10.1371/journal.pone.0150606. eCollection 2016.
2	Development and maintenance of intestinal regulatory T cells.Nat Rev Immunol. 2016 May;16(5):295-309. doi: 10.1038/nri.2016.36. Epub 2016 Apr 18.

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