General Information of HIF (ID: HIFM0010)
HIF Name	Natural killer cell receptor BY55
HIF Synonym(s)	BY55, CD160
HIF Classification	Checkpoint molecule (CM)
Molecular Function	Receptor
Description	CD160 is expressed on T cells to regulate responses to self-proteins.				[1]
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	BY55_HUMAN

Microbe Species (MIC) Regulated by This HIF
Clostridioides difficile (firmicutes)			MIC00396
Description	CD160 is responsible for a significant fraction of the colonic STAT3 phosphorylation in Clostridium difficile infection.				[2]

References
1	Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy.Clin Cancer Res. 2013 Sep 15;19(18):4917-24. doi: 10.1158/1078-0432.CCR-12-1972. Epub 2013 Jul 18.
2	Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.Immunology. 2015 Apr;144(4):587-97. doi: 10.1111/imm.12414.

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