Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)
| General Information of HIF (ID: HIFM0131) | |||||
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| HIF Name |
Interleukin-12 subunit beta
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| HIF Synonym(s) |
interleukin 12b, Il12b, p40, Il-12b, Il12p40, Il-12p40
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| HIF Classification |
Cytokine (Cyt)
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| Molecular Function |
Cytokine
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| Description | IL-12p40 plays an important role in the activation of the T-cell lines like Th17 and Th1-cells. | [1] | |||
| Pfam | Cytokine interleukin-12p40 C-terminus (PF10420 ) | ||||
| Pathway | African trypanosomiasis (hsa05143 ) | ||||
| Allograft rejection (hsa05330 ) | |||||
| Amoebiasis (hsa05146 ) | |||||
| C-type lectin receptor signaling pathway (hsa04625 ) | |||||
| Chagas disease (American trypanosomiasis) (hsa05142 ) | |||||
| Cytokine-cytokine receptor interaction (hsa04060 ) | |||||
| Herpes simplex virus 1 infection (hsa05168 ) | |||||
| Inflammatory bowel disease (IBD) (hsa05321 ) | |||||
| Influenza A (hsa05164 ) | |||||
| JAK-STAT signaling pathway (hsa04630 ) | |||||
| Legionellosis (hsa05134 ) | |||||
| Leishmaniasis (hsa05140 ) | |||||
| Measles (hsa05162 ) | |||||
| Pathways in cancer (hsa05200 ) | |||||
| Pertussis (hsa05133 ) | |||||
| Proteoglycans in cancer (hsa05205 ) | |||||
| RIG-I-like receptor signaling pathway (hsa04622 ) | |||||
| Th1 and Th2 cell differentiation (hsa04658 ) | |||||
| Toll-like receptor signaling pathway (hsa04620 ) | |||||
| Toxoplasmosis (hsa05145 ) | |||||
| Tuberculosis (hsa05152 ) | |||||
| Type I diabetes mellitus (hsa04940 ) | |||||
| Sequence | Click here to download the HIF sequence in FASTA format | ||||
| External Links | |||||
| Uniprot ID | |||||
| Microbe Species (MIC) Regulated by This HIF | |||||
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| Parabacteroides distasonis (CFB bacteria) | MIC00949 | ||||
| Description | Parabacteroides distasonis is associated with interleukin (IL)-l12p40p70. | [2] | |||
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