Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0164)
HIF Name
Lymphocyte function-associated antigen 3
HIF Synonym(s)
Ag3, LFA3, CD58
HIF Classification
Checkpoint molecule (CM)
Description CD58 is reported to be crucial immune modulator. [1]
Pathway Cell adhesion molecules (CAMs) (hsa04514 )
Epstein-Barr virus infection (hsa05169 )
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
LFA3_HUMAN
Microbe Species (MIC) Regulated by This HIF
         Escherichia coli (enterobacteria) MIC00516
             Description The abundance of Escherichia coli is associated with CD58 activation. [2]
References
1 Exploration of a novel prognostic risk signatures and immune checkpoint molecules in endometrial carcinoma microenvironment.Genomics. 2020 Sep;112(5):3117-3134. doi: 10.1016/j.ygeno.2020.05.022. Epub 2020 May 29.
2 Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies.EMBO J. 1999 Jun 1;18(11):2941-9. doi: 10.1093/emboj/18.11.2941.

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