Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0244)
HIF Name	C motif chemokine 1
HIF Synonym(s)	X-C motif chemokine ligand 1, ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1
HIF Classification	Cytokine (Cyt)
Molecular Function	Cytokine
Description	XCL1, also known as lymphotactin, is an inflammatory chemokine secreted by T cells and natural killer(NK) cells.		[1]
Pfam	Small cytokines (intecrine/chemokine), interleukin-8 like (PF00048 )
Pathway	Chemokine signaling pathway (hsa04062 )
	Cytokine-cytokine receptor interaction (hsa04060 )
	Viral protein interaction with cytokine and cytokine receptor (hsa04061 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
External Links	Uniprot ID	XCL1_HUMAN

Microbe Species (MIC) Regulated by This HIF
Mycobacterium ulcerans (actinobacteria)		MIC00852
Description	Mycobacterium marinum could cause higher expression of chemokines including XCL1.		[2]

References
1	XCL1 and XCR1 in the immune system.Microbes Infect. 2012 Mar;14(3):262-7. doi: 10.1016/j.micinf.2011.10.003. Epub 2011 Oct 31.
2	Mycobacterium marinum: a potential immunotherapy for Mycobacterium tuberculosis infection. Drug Des Devel Ther. 2013 Jul 29;7:669-80. doi: 10.2147/DDDT.S45197. Print 2013.

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