General Information of HIF (ID: HIFM0315)
HIF Name	Neurotensin
HIF Synonym(s)	Neurotensin, Neurotensin
HIF Classification	Antimicrobial peptide (AMP)
Description	Neurotensin has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
External Links
	APD ID	AP01471

Microbe Species (MIC) Regulated by This HIF
Bacteroidetes (CFB bacteria)			MIC00141
Description	HFD-fed neurotensin+/+ mice had a significantly decreased abundance of the general Odoribacter (belonging to Bacteroidetes phylum).				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Absence of neurotensin attenuates intestinal dysbiosis and inflammation by maintaining Mmp7/-defensin axis in diet-induced obese mice.FASEB J. 2020 Jun;34(6):8596-8610. doi: 10.1096/fj.201902374RR. Epub 2020 May 2.

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