Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFP0049)
HIF Name	Toll-like receptor 6 signaling pathway
HIF Synonym(s)	TLR6 signalling, TLR6 signaling pathway
HIF Classification	Signaling pathway (SP)
Description	The activation of the TLR signaling pathway originates from the cytoplasmic Toll/IL-1 receptor (TIR) domain that associates with a TIR domain-containing adaptor, MyD88.	[1]

Microbe Species (MIC) Regulated by This HIF
Lactobacillus gallinarum (firmicutes)		MIC00715
Description	Enterococcus gallinarum strain is a potent inducer of cytokines and TLR6 signalling.		[2]

References
1	gga-miR-146c Activates TLR6/MyD88/NF-B Pathway through Targeting MMP16 to Prevent Mycoplasma Gallisepticum (HS Strain) Infection in Chickens.Cells. 2019 May 24;8(5):501. doi: 10.3390/cells8050501.
2	Immunomodulatory properties of Streptococcus and Veillonella isolates from the human small intestine microbiota. PLoS One. 2014 Dec 5;9(12):e114277. doi: 10.1371/journal.pone.0114277. eCollection 2014.

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