Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00207)
MIC Name Bifidobacterium animalis (actinobacteria)
MIC Synonyms Bifidobacterium longum subsp. animalis biotype a
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: Bifidobacterium animalis
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Positive
Host Relationship Probiotic
Genome Size (bp) 1931057
No. of Coding Genes 1539
No. of Non-Coding Genes 61
No. of Small Non-Coding Genes 61
No. of Gene Transcripts 1600
No. of Base Pairs 1931057
Description Bifidobacterium animalis is a branched, rod-shaped (diplobicillus) obligate anaerobic Gram-positive bacteria. This bacteria is generally found in the large intestines of mammals such as cats, cows, and humans. Bifidobacterium animalis is now comprised of two subspecies Bifidobacterium animalis subsp. lactis and Bifidobacterium animalis subsp. animalis. It was found a beneficial probiotic for human.
External Links Taxonomy ID
28025
Genome Assembly ID
ASM69589v1
GOLD Organism ID
Go0002199
Disease Relevance
          Colorectal cancer  [ICD-11: 2B91]
             Description The numbers of Bifidobacterium animalis were decreased in feces from patients with colorectal adenoma or cancer. [1]
          Vibrio mimicus gastroenteritis  [ICD-11: 1A40]
             Description Bifidobacterium animalis, a traditional probiotic species that was expanded in experimental colitis, induced marked duodenal and mild colonic inflammation. [2]
Host Genetic Factors (HGFs)
          rs651821
             HGF ID HGF1924 HGF Info       Class Single Nucleotide Polymorphism: Prime UTR variant (SNP-PV)
             Description The APOA5 SNP rs651821 might be an important host genetic factor in determining the abundances of the health-promoting Bifidobacterium bacteria and the taxa to which this genus belongs. [3]
          rs2284553
             HGF ID HGF2616 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs2284553 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs1042058
             HGF ID HGF2617 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-SV)
             Description The rs1042058 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs2816958
             HGF ID HGF2538 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs2816958 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs12568930
             HGF ID HGF2533 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs12568930 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs3851228
             HGF ID HGF2553 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs3851228 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs6740462
             HGF ID HGF2537 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs6740462 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs7608910
             HGF ID HGF2613 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs7608910 SNP is associated with the abundance of Bifidobacterium animalis. [4]
          rs11054935
             HGF ID HGF2618 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs11054935 SNP is associated with the abundance of Bifidobacterium animalis. [4]
Environmental Factor(s)
             Disbiome ID
      764
             gutMDisorder ID
      gm0107
References
1 Intestinal microbiota, chronic inflammation, and colorectal cancer. Intest Res. 2018 Jul;16(3):338-345. doi: 10.5217/ir.2018.16.3.338. Epub 2018 Jul 27.
2 Bifidobacterium animalis causes extensive duodenitis and mild colonic inflammation in monoassociated interleukin-10-deficient mice. Inflamm Bowel Dis. 2009 Jul;15(7):1022-31. doi: 10.1002/ibd.20900.
3 The effect of heritability and host genetics on the gut microbiota and metabolic syndrome.Gut. 2017 Jun;66(6):1031-1038. doi: 10.1136/gutjnl-2015-311326. Epub 2016 Apr 6.
4 A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice. Genetics. 2020 Mar;214(3):719-733. doi: 10.1534/genetics.119.303013. Epub 2020 Jan 2.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.