Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00253)
MIC Name Borreliella garinii (spirochaetes)
MIC Synonyms Borrelia genomic group 20047
Body Site Skin
Lineage Kingdom: Bacteria
Phylum: Spirochaetes
Class: Spirochaetia
Order: Spirochaetales
Family: Borreliaceae
Genus: Borreliella
Species: Borreliella garinii
Oxygen Sensitivity Anaerobe; Microaerophilic
Microbial Metabolism Saccharolytic
Gram Negative
Host Relationship Pathogen
Genome Size (bp) 4304348
No. of Coding Genes 4117
No. of Non-Coding Genes 49
No. of Small Non-Coding Genes 49
No. of Gene Transcripts 4166
No. of Base Pairs 4304348
Description Borrelia garinii is generally characterized to be an anaerobic or microaerophilic, spiral shaped, motile, non-capsulated, non-sporing spirochete. It can cause lyme disease.
External Links Taxonomy ID
29519
Genome Assembly ID
ASM78753v1
GOLD Organism ID
Go0519497
Disease Relevance
          Flegel disease  [ICD-11: ED5Y]
             Description Borrelia garinii was associated with flegel disease. [1]
          Lyme borreliosis  [ICD-11: 1C1G]
             Description Borrelia garinii can cause Lyme disease. [2]
Host Genetic Factors (HGFs)
          rs41289586
             HGF ID HGF1927 HGF Info       Class Single Nucleotide Polymorphism: Missense variant (SNP-MV)
             Description The rs41289586 SNP was significantly associated with the abundance of Borrelia garinii (p-value=7.18E-08). [3]
          rs17850869
             HGF ID HGF1225 HGF Info       Class Single Nucleotide Polymorphism: Synonymous variant (SNP-SV)
             Description The rs17850869 SNP was significantly associated with the abundance of Borrelia garinii (p-value=4.17E-09). [3]
References
1 Detection of Borrelia burgdorferi sensu stricto and Borrelia garinii DNAs in patient with Hyperkeratosis lenticularis perstans (Flegel disease). Folia Microbiol (Praha). 2016 Sep;61(5):359-63. doi: 10.1007/s12223-016-0444-0. Epub 2016 Jan 15.
2 Clinical spectrum of Lyme disease. Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):201-208. doi: 10.1007/s10096-018-3417-1. Epub 2018 Nov 19.
3 A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity.Mol Med. 2015 Feb 23;21(1):26-37. doi: 10.2119/molmed.2014.00219.

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