General Information of MIC (ID: MIC00335)
MIC Name	Catonella morbi (firmicutes)
Body Site	Oral Cavity
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Clostridia Order: Clostridiales Family: Lachnospiraceae Genus: Catonella Species: Catonella morbi
Oxygen Sensitivity	Strictly anaerobe
Microbial Metabolism	Saccharolytic; Fermentative
Gram	Negative
Host Relationship	Pathogen
Genome Size (bp)	3477404
Description	Catonella morbi is a strictly anaerobic, Gram negative, rods. As of this time, it has only been isolated from humans, specifically from the oral cavity. It has been cited to be one of many bacteria behind endodontic infections and periodontitis.
External Links	Taxonomy ID	43997
	Genome Assembly ID	ASM16003v2
	GOLD Organism ID	Go0068196
Disease Relevance
Periodontal disease  [ICD-11: DA0C]
Description	Catonella morbi was associated with periodontitis.				[1]
Periodontal disease  [ICD-11: DA0C]
Description	Catonella morbi can take part in the microbiota associated with primary endodontic infection.				[1]

Host Genetic Factors (HGFs)
MIR21
HGF ID	HGF2332	HGF Info	Class	Copy Number Variation: Gene Deletion (CNV-GDe)
Description	The deletion of MIR-21 was significantly increased the proportion of Catonella (p-value<0.05).				[2]

Environmental Factor(s)
Disbiome ID			898

References
1	Catonella morbi and Granulicatella adiacens: new species in endodontic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Aug;102(2):259-64. doi: 10.1016/j.tripleo.2005.09.021. Epub 2006 Apr 21.
2	Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis.J Crohns Colitis. 2018 Jun 28;12(7):835-848. doi: 10.1093/ecco-jcc/jjy038.

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