General Information of MIC (ID: MIC00383)
MIC Name	Enterocloster bolteae (firmicutes)
MIC Synonyms	Clostridium bolteae
Body Site	Gut
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Clostridia Order: Clostridiales Family: Lachnospiraceae Genus: Enterocloster Species: Enterocloster bolteae
Oxygen Sensitivity	Obligate anaerobe
Microbial Metabolism	Saccharolytic; Fermentative
Gram	Positive
Host Relationship	Commensal
Description	Clostridium bolteae is a Gram-positive, obligately anaerobic, spore-forming and rod-shaped bacterium from the genus of Clostridium which has been isolated from human faeces. This bacterium was found associated with chronic diarrheal.
External Links	Taxonomy ID	208479
	Genome Assembly ID	ASM223457v2
Disease Relevance
Irritable bowel syndrome  [ICD-11: DD91]
Description	Chronic diarrheal episodes associated with some forms of autism could be attributed to an overabundance of Clostridium bolteae and release of end products of metabolism.				[1]

Host Genetic Factors (HGFs)
rs7297871
HGF ID	HGF1828	HGF Info	Class	Single Nucleotide Polymorphism: Intron variant (SNP-IV)
Description	The rs7297871 SNP is significantly associated with the abundance of Clostridium bolteae (p-value=4.21E-05).				[2]

Environmental Factor(s)
Disbiome ID			47
gutMDisorder ID			gm0190

References
1	Comparative genomics of Clostridium bolteae and Clostridium clostridioforme reveals species-specific genomic properties and numerous putative antibiotic resistance determinants. BMC Genomics. 2016 Oct 21;17(1):819. doi: 10.1186/s12864-016-3152-x.
2	Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD.Gut. 2020 Jul 10:gutjnl-2019-319706. doi: 10.1136/gutjnl-2019-319706. Online ahead of print.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.