| General Information of MIC (ID: MIC00397) |
| MIC Name |
Hungatella hathewayi (firmicutes)
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| MIC Synonyms |
Clostridium hathewayi
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Clostridiaceae
Genus: Hungatella
Species: Hungatella hathewayi
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| Oxygen Sensitivity |
Obligate anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Negative
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| Description |
Hungatella hathewayi is a newly described gut commensal that stains Gram-negative.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| 15q11-13 |
| HGF ID |
HGF2318 |
HGF Info
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Class |
Copy Number Variation: Gene Duplication (CNV-GDu) |
| Description |
There hao a significantly different abundance of Clostridium hathewayi between 15q dup mice and wide type littermates (p-value=0.0137). |
[1] |
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| Host Immune Factors (HIFs) |
| CD4+ helper T cells |
| HIF ID |
HIFC0068 |
HIF Info
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Class |
T cells (TCs) |
| Description |
Hungatella hathewayi is a low secretor of IL-10 on the Th1-driven inflammatory response to DNBS. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| References |
| 1 |
Altered microbiota composition reflects enhanced communication in 15q11-13 CNV mice.Neurosci Res. 2019 Dec 18:S0168-0102(19)30671-6. doi: 10.1016/j.neures.2019.12.010. Online ahead of print.
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| 2 |
Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses. Sci Rep. 2016 Jan 4;6:18507. doi: 10.1038/srep18507.
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