General Information of MIC (ID: MIC00511)
MIC Name Dorea formicigenerans (firmicutes)
MIC Synonyms Eubacterium formicigenerans
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Lachnospiraceae
Genus: Dorea
Species: Dorea formicigenerans
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Positive
Genome Size (bp) 3186031
Description Dorea formicigenerans is a Gram-positive, obligately anaerobic, non-spore-forming and rod-shaped bacterium from the genus of Dorea which occur in human faeces
External Links Taxonomy ID
39486
Genome Assembly ID
ASM16923v1
GOLD Organism ID
Go0000907
Disease Relevance
          Psoriatic arthritis  [ICD-11: FA21]
             Description The psoriatic patients showed significant increases in the relative proportions of Dorea formicigenerans. [1]
Host Genetic Factors (HGFs)
          rs230663
             HGF ID HGF1695 HGF Info       Class Single Nucleotide Polymorphism: Prime UTR variant (SNP-PV)
             Description with the minor C allele. [2]
          rs2457996
             HGF ID HGF2540 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs2457996 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs7608910
             HGF ID HGF2613 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs7608910 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs2266959
             HGF ID HGF2628 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs2266959 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs17229285
             HGF ID HGF2578 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs17229285 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs11054935
             HGF ID HGF2618 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs11054935 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs477515
             HGF ID HGF2629 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs477515 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs4656958
             HGF ID HGF2630 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-UV)
             Description The rs4656958 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs6708413
             HGF ID HGF2544 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs6708413 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs2111485
             HGF ID HGF2546 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs2111485 SNP is associated with the abundance of Dorea formicigenerans. [3]
          rs7495132
             HGF ID HGF2631 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs7495132 SNP is associated with the abundance of Dorea formicigenerans. [3]
Environmental Factor(s)
             Disbiome ID
      295
             gutMDisorder ID
      gm0266
References
1 Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls. J Dermatol. 2019 Jul;46(7):595-603. doi: 10.1111/1346-8138.14933. Epub 2019 May 29.
2 Host genetic variation and its microbiome interactions within the Human Microbiome Project.Genome Med. 2018 Jan 29;10(1):6. doi: 10.1186/s13073-018-0515-8.
3 A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice. Genetics. 2020 Mar;214(3):719-733. doi: 10.1534/genetics.119.303013. Epub 2020 Jan 2.

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