| General Information of MIC (ID: MIC00957) |
| MIC Name |
Paraprevotella (CFB bacteria)
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| Body Site |
Mucosa
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| Lineage |
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Prevotellaceae
Genus: Paraprevotella
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Negative
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| Description |
The anaerobic, Gram negative genus Paraprevotella comprises 0.5% of total bacteria in the gut.
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| External Links |
Taxonomy ID |
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| Disease Relevance |
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| Chronic kidney disease [ICD-11: GB61] |
| Description |
Paraprevotella was negatively correlated with CKD(Chronic kidney disease) severity. |
[1] |
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| Host Genetic Factors (HGFs) |
| rs571312 |
| HGF ID |
HGF2159 |
HGF Info
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Class |
Single Nucleotide Polymorphism (SNP) |
| Description |
The variant gene MC4R of innate immunity rs571312 is significantly associated with the abundance of gut micriobiota Paraprevotella (p-value=0.0139). |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Gut Microbiota as Diagnostic Tools for Mirroring Disease Progression and Circulating Nephrotoxin Levels in Chronic Kidney Disease: Discovery and Validation Study. Int J Biol Sci. 2020 Jan 1;16(3):420-434. doi: 10.7150/ijbs.37421. eCollection 2020.
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| 2 |
Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
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