| General Information of MIC (ID: MIC01132) |
| MIC Name |
Ruminococcus albus (firmicutes)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Ruminococcaceae
Genus: Ruminococcus
Species: Ruminococcus albus
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| Oxygen Sensitivity |
Obligate anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Positive
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| Genome Size (bp) |
4326500
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| Description |
Ruminococcus albus is an obligate anaerobe and Gram-positive bacterium.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Disease Relevance |
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| Ulcerative colitis [ICD-11: DD71] |
| Description |
Ulcerative colitis was associated with Ruminococcus albus infection. |
[1] |
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| Host Genetic Factors (HGFs) |
| rs2066842 |
| HGF ID |
HGF1456 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Missense variant (SNP-MV) |
| Description |
The variant gene NOD2 of innate immunity rs2066842 is significantly associated with the abundance of gut micriobiota Ruminococcus albus (p-value<0.0001). |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Longitudinal analyses of gut mucosal microbiotas in ulcerative colitis in relation to patient age and disease severity and duration. J Clin Microbiol. 2013 Mar;51(3):849-56. doi: 10.1128/JCM.02574-12. Epub 2012 Dec 26.
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| 2 |
Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
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