Drug Information

Drug General Information
Drug ID
D02CJA
Former ID
DIB010517
Drug Name
CM-2236
Synonyms
Psychomodulator (post-traumatic stress disorder), Cenomed BioSciences
Indication Post-traumatic stress disorder [ICD9: 309.81; ICD10:F43.1] Preclinical [548834]
Company
Cenomed BioSciences LLC
Target and Pathway
Target(s) Alpha-1A adrenergic receptor Target Info Agonist [550867]
5-hydroxytryptamine 1A receptor Target Info Agonist [550867]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Salivary secretionhsa04024:cAMP signaling pathway
Serotonergic synapse
PANTHER Pathway Alpha adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Adrenoceptors
G alpha (q) signalling events
G alpha (12/13) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Endothelin Pathways
GPCR ligand binding
GPCR downstream signaling
AMPK SignalingWP722:Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
References
Ref 548834Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029346)
Ref 550867CN patent application no. 104151292, Indole derivative or a pharmaceutically acceptable salt thereof.

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