Drug Information

Drug General Information
Drug ID
D03RZM
Former ID
DIB002462
Drug Name
Steroid hormone conjugates
Synonyms
AM-454; Steroid hormone conjugates (diabetes); DHEA-PC, AMUR; DHEA-PC, SuperGen; DHEA-phosphocoline, SuperGen; Steroid hormone conjugates (diabetes), SuperGen
Indication Cachexia [ICD9: 799.4; ICD10:R64] Terminated [547402]
Company
AMUR Pharmaceuticals Inc
Target and Pathway
Target(s) Steroid hormone receptor ERR1 Target Info Modulator [534809]
Reactome PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Nuclear Receptor transcription pathway
WikiPathways Mitochondrial Gene Expression
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Nuclear Receptors
References
Ref 547402Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015954)
Ref 534809The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf). 1998 Oct;49(4):421-32.

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