Drug Information

Drug General Information
Drug ID
D04LSH
Former ID
DND000087
Drug Name
SAR101099
Indication Diabetic nephropathy [ICD9: 250.4; ICD10:E11.21] Discontinued in Phase 1 [549207]
Company
Sanofi
Target and Pathway
Target(s) Urotensin II receptor Target Info Antagonist [543795]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 549207Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033702)
Ref 543795(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 365).

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