Drug Information

Drug General Information
Drug ID
D06CNP
Drug Name
Abiraterone acetate
Synonyms
CB-7630; JNJ-212082; Zytiga
Drug Type
Small molecular drug
Indication Metastatic castration-resistant prostate cancer [ICD9: 140-229, 185; ICD10:C61] Approved [551871]
Therapeutic Class
Anticancer Agents
Formula
C26H33NO2
PubChem Compound ID
9821849
Target and Pathway
Target(s) 17 alpha-hydroxylase-C17, 20-lyase Target Info Modulator
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Glucocorticoid biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesis
Metabolic pathways
Ovarian steroidogenesis
Prolactin signaling pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
Steroidogenesis
Reactome Androgen biosynthesis
Glucocorticoid biosynthesis
Endogenous sterols
WikiPathways Metapathway biotransformation
Steroid Biosynthesis
Oxidation by Cytochrome P450
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
Prostate Cancer
Phase 1 - Functionalization of compounds
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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