Drug Information

Drug General Information
Drug ID
D08MTG
Former ID
DIB003924
Drug Name
Abafungin
Synonyms
Abasol; W-634; YP-006; YP-007; Abafungin (gel formulation), York Pharma; Abafungin (cream, dermatomycosis), York Pharma; Abafungin (gel formulation, onychomycosis), York Pharma; Abafungin (pessary, vaginal candidiasis), York Pharma
Drug Type
Small molecular drug
Indication Fungal infections [ICD9: 110-118; ICD10:B35-B49] Discontinued in Phase 3 [548190]
Company
York Pharma
Formula
C21H22N4OS
Canonical SMILES
c1(nc(c2c(Oc3c(cc(cc3)C)C)cccc2)cs1)NC1=NCCCN1
CAS Number
CAS 129639-79-8
PubChem Compound ID
159326
Target and Pathway
Target(s) Fungal Cytochrome P450 51 Target Info Inhibitor [527740]
References
Ref 548190Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022887)
Ref 527740Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors. Mol Biochem Parasitol. 2005 Nov;144(1):68-75.

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