TTD | Drug: D0T2QN

Drug General Information
Drug ID	D0T2QN
Former ID	DIB010174
Drug Name	PF-2393296
Synonyms	IDDBCP185108
Indication	Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0]		Discontinued in Phase 1	[548716]
Company	Pfizer Inc
Canonical SMILES	C1N[C@@H](C[C@@H]1Cc1cccc(c1)F)C(=O)O
Target and Pathway
Target(s)	GABA A receptor delta subunit	Target Info	Agonist	[543815]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
References
Ref 548716	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027949)
Ref 543815	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 416).

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Drug Information