Drug Information

Drug General Information
Drug ID
D0X2NB
Former ID
DIB011051
Drug Name
AZD-6319
Synonyms
Alpha 7 neuronal nicotinic receptor agonist (Alzheimer's disease), AstraZeneca
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Investigative [543845]
Company
AstraZeneca plc
Target and Pathway
Target(s) Neuronal acetylcholine receptor protein, alpha-7 chain Target Info Agonist [543845]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addiction
Chemical carcinogenesis
PANTHER Pathway Alzheimer disease-amyloid secretase pathway
Nicotinic acetylcholine receptor signaling pathway
Reactome Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 543845(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 468).
Ref 543845(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 468).

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