Drug Information

Drug General Information
Drug ID
D0Y1WV
Former ID
DNC000523
Drug Name
DCG IV
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538854]
Formula
C7H9NO6
InChI
InChI=1S/C7H9NO6/c8-4(7(13)14)1-2(5(9)10)3(1)6(11)12/h1-4H,8H2,(H,9,10)(H,11,12)(H,13,14)/t2-,3-,4+/m1/s1
InChIKey
MATPZHBYOVDBLI-JJYYJPOSSA-N
CAS Number
CAS 147782-19-2
PubChem Compound ID
5310979
PubChem Substance ID
7978575, 11056183, 15220055, 15220056, 39340713, 76023416, 103204644, 103942697, 114154965, 128568778, 135650164, 137133023, 144223858, 163306193, 226956019, 241037206
Target and Pathway
Target(s) Metabotropic glutamate receptor 2 Target Info Agonist [535209]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
Cocaine addiction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group II pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 538854(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1377).
Ref 535209Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists. Brain Res. 2001 Jul 27;908(2):120-9.

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