Drug Information

Drug General Information
Drug ID
D09VTR
Former ID
DNC012943
Drug Name
4-(4-tert-butylbenzylthio)-2-aminobutanoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527946]
Formula
C15H23NO2S
Canonical SMILES
CC(C)(C)C1=CC=C(C=C1)CSCCC(C(=O)O)N
InChI
1S/C15H23NO2S/c1-15(2,3)12-6-4-11(5-7-12)10-19-9-8-13(16)14(17)18/h4-7,13H,8-10,16H2,1-3H3,(H,17,18)
InChIKey
BAHGAZBQXUXBJR-UHFFFAOYSA-N
PubChem Compound ID
44408220
Target and Pathway
Target(s) Voltage-dependent calcium channel subunit alpha-2/delta-1 Target Info Inhibitor [527946]
KEGG Pathway MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
PANTHER Pathway Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways Arrhythmogenic Right Ventricular Cardiomyopathy
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 527946Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
Ref 527946Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

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