TTD | Drug: D0G2XN

Drug General Information
Drug ID	D0G2XN
Former ID	DIB014536
Drug Name	S-12968
Synonyms	Olradipine; Pranedipine; (-)-S 12968
Drug Type	Small molecular drug
Indication	Hypertension [ICD9: 401; ICD10:I10-I16]		Discontinued in Phase 3	[544583]
Company	Servier
Formula	C26H34Cl2N2O12
Canonical SMILES	C1(=C(NC(=C([C@@H]1c1c(c(Cl)ccc1)Cl)C(=O)OCC)COCCOCCN)C<br />)C(=O)OC
CAS Number	CAS 132194-66-2
PubChem Compound ID	6918192
Target and Pathway
Target(s)	Calcium channel	Target Info	Blocker	[530048]
References
Ref 544583	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000221)
Ref 530048	(+)-S-12967 and (-)-S-12968: 1,4-dihydropyridine stereoisomers with calcium channel agonistic and antagonistic properties in rat resistance arteries. Br J Pharmacol. 1991 Jul;103(3):1703-8.

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Drug Information