Drug Information

Drug General Information
Drug ID
D07BKR
Former ID
DNCL002295
Drug Name
ARQ 621
Drug Type
Small molecular drug
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Phase 1 [522550]
Company
ArQule
Formula
C28H24Cl2FN5O2
PubChem Compound ID
25110841
Target and Pathway
Target(s) Kinesin-like protein KIF11 Target Info Modulator [531974]
Reactome MHC class II antigen presentation
Kinesins
WikiPathways MHC class II antigen presentation
Kinesins
References
Ref 522550ClinicalTrials.gov (NCT00825487) Dose Escalation Study of ARQ 621 in Adult Patients With Metastatic Solid Tumors and Hematologic Malignancies. U.S. National Institutes of Health.
Ref 531974Kinesins and cancer. Nat Rev Cancer. 2012 Jul 24;12(8):527-39.

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