Drug Information

Drug General Information
Drug ID
D06UXL
Former ID
DIB014087
Drug Name
GI-248573
Indication Bladder disease [ICD10:N30-N32] Terminated [546536]
Company
Glaxo Wellcome plc
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Modulator [550839]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 546536Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008844)
Ref 550839US patent application no. 8,748,419, Antagonists.

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