Drug Information

Drug General Information
Drug ID
D08FTP
Former ID
DIB006115
Drug Name
99mTc-MIP-1404
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 2 [524028]
Company
Molecular Insight Pharmaceuticals Inc
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info Modulator [532384]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 524028ClinicalTrials.gov (NCT01667536) A Phase 2 Diagnostic Imaging Study With 99mTc-MIP-1404 in Men With High-Risk Prostate Cancer Scheduled for Radical Prostatectomy (RP) and Extended Pelvic Lymph Node Dissection (EPLND) Compared to Histopathology. U.S. National Institutes of Health.
Ref 53238499mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer. J Nucl Med. 2013 Aug;54(8):1369-76.

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