Drug Information

Drug General Information
Drug ID
D0D7YA
Former ID
DIB015595
Drug Name
DSP-6952
Synonyms
Serotonin 4 receptor partial agonist (constipation), Dainippon Sumitomo
Indication Constipation [ICD9: 564; ICD10:K59.0] Phase 2 [549293]
Company
Dainippon Sumitomo Pharma Co Ltd
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Agonist [550349]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 549293Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034751)
Ref 550349DSP-6952, a high affinity serotonin (5-HT4) receptor partial agonist. Sumitomo Dainippon Pharma Co. Ltd.

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