Drug Information

Drug General Information
Drug ID
D01TLV
Former ID
DNCL001655
Drug Name
EVT 401
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Phase 1 [551888]
Company
Evotec
Target and Pathway
Target(s) P2X purinoceptor 7 Target Info Antagonist [544235]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome The NLRP3 inflammasome
WikiPathways Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
References
Ref 551888Clinical pipeline report, company report or official report of Evotec.
Ref 544235Molecular and functional properties of P2X receptors??ecent progress and persisting challenges. Purinergic Signal. 2012 September; 8(3): 375-417.

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