Drug Information

Drug General Information
Drug ID
D0Y5NT
Former ID
DIB002249
Drug Name
VT-224
Synonyms
Cc-chemokine binding protein (inflammation), Viron
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Investigative [543912]
Company
Viron Therapeutics Inc
Target and Pathway
Target(s) CC chemokine receptor Target Info Modulator [543912]
KEGG Pathway Cytokine-cytokine receptor interaction
Chemokine signaling pathway
Reactome Beta defensins
Binding and entry of HIV virion
Chemokine receptors bind chemokines
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543912(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 67).
Ref 543912(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 67).

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