Target Information

Target General Infomation
Target ID
T37536
Former ID
TTDI03545
Target Name
sigma2
Target Type
Research
Agonist 1,3-ditolylguanidine Drug Info [528020]
[3H]-di-o-tolylguanidine Drug Info [543647]
Antagonist SM 21 Drug Info [525452]
References
Ref 525452The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors. Life Sci. 1999;64(10):PL131-7.
Ref 528020Sigma1 and sigma2 receptor binding affinity and selectivity of SA4503 and fluoroethyl SA4503. Synapse. 2006 May;59(6):350-8.
Ref 543647(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2553).

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