Drug Information

Drug General Information
Drug ID
D02EOS
Former ID
DND000016
Drug Name
CVX-241
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [544157]
Company
Pfizer
Target and Pathway
Target(s) Angiopoietin-2 Target Info Modulator [544157]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Angiogenesis
Pathway Interaction Database Angiopoietin receptor Tie2-mediated signaling
Reactome Tie2 Signaling
WikiPathways Cell surface interactions at the vascular wall
References
Ref 544157Chemical generation of bispecific antibodies. Proc Natl Acad Sci U S A. 2010 December 28; 107(52): 22611-22616.
Ref 544157Chemical generation of bispecific antibodies. Proc Natl Acad Sci U S A. 2010 December 28; 107(52): 22611-22616.

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