Drug Information

Drug General Information
Drug ID
D02RMS
Former ID
DNC011855
Drug Name
Ethyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533152]
Formula
C9H15N3
Canonical SMILES
CCNC1CCC2=C(C1)C=NN2
InChI
1S/C9H15N3/c1-2-10-8-3-4-9-7(5-8)6-11-12-9/h6,8,10H,2-5H2,1H3,(H,11,12)
InChIKey
DDFOVLJCDZCIIF-UHFFFAOYSA-N
PubChem Compound ID
14539718
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [533152]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 533152J Med Chem. 1989 Oct;32(10):2388-96.Substituted 5-amino-4,5,6,7-tetrahydroindazoles as partial ergoline structures with dopaminergic activity.
Ref 533152J Med Chem. 1989 Oct;32(10):2388-96.Substituted 5-amino-4,5,6,7-tetrahydroindazoles as partial ergoline structures with dopaminergic activity.

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