Drug Information

Drug General Information
Drug ID
D03MYO
Former ID
DIB001166
Drug Name
MGL-3196
Indication Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] Phase 1 [532494]
Company
Madrigal pharmaceuticals
Target and Pathway
Target(s) Thyroid hormone receptor beta-1 Target Info Agonist [532494]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 532494Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-beta agonist. Atherosclerosis. 2013 Oct;230(2):373-80.
Ref 532494Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-beta agonist. Atherosclerosis. 2013 Oct;230(2):373-80.

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