Drug Information

Drug General Information
Drug ID
D04YJO
Former ID
DIB011218
Drug Name
CGS-19480A
Synonyms
3-(Dipropylamino)-5-ethoxy-3,4-dihydro-2H-[1]-benzothiopyran hydrochloride
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Investigative [550159], [551871]
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Modulator [550159], [551871]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 550159WO patent application no. 2012,0025,83, Method for treating schizophrenia and related diseases with a combination therapy.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 550159WO patent application no. 2012,0025,83, Method for treating schizophrenia and related diseases with a combination therapy.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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