Drug Information

Drug General Information
Drug ID
D07EJY
Former ID
DIB006043
Drug Name
AR-12286
Synonyms
AR-11236; AR-12080; AR-12132; CF-286-03; CF-286-04
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Phase 2 [524084]
Company
Aerie Pharmaceuticals Inc
Canonical SMILES
c1nccc2c1ccc(c2)NC(=O)C(CC1CCCCC1)NC
Target and Pathway
Target(s) Rho associated protein kinase Target Info Modulator [531577]
References
Ref 524084ClinicalTrials.gov (NCT01699464) A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months. U.S. National Institutes of Health.
Ref 531577Ocular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension. Am J Ophthalmol. 2011 Nov;152(5):834-41.e1.

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