Drug Information

Drug General Information
Drug ID
D0J2NS
Former ID
DNC000223
Drug Name
Anti-D
Drug Type
Small molecular drug
Indication Idiopathic thrombocytopenic purpura [ICD9: 287.31; ICD10:D69.3] Investigative [536737]
Formula
C6H14ClNO5
Canonical SMILES
C(C1C(C(C(C(O1)O)N)O)O)O.Cl
InChI
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6-;/m1./s1
InChIKey
QKPLRMLTKYXDST-OCOFDJSDSA-N
CAS Number
CAS 66-84-2
PubChem Compound ID
9859210
PubChem Substance ID
14822544, 24152610, 26611758, 26679579, 29204185, 45281506, 57373577, 75124350, 92123957, 124637435, 134339710, 144075063, 162093875, 226410542
SuperDrug ATC ID
M01AX05
SuperDrug CAS ID
cas=003416248
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Antagonist [536737]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 536737Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.
Ref 536737Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.

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