Drug Information

Drug General Information
Drug ID
D0R9KV
Former ID
DNC012557
Drug Name
3-(2,5-Dimethyl-phenyl)-1-propyl-piperidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534764]
Formula
C16H25N
Canonical SMILES
CCCN1CCCC(C1)C2=C(C=CC(=C2)C)C
InChI
1S/C16H25N/c1-4-9-17-10-5-6-15(12-17)16-11-13(2)7-8-14(16)3/h7-8,11,15H,4-6,9-10,12H2,1-3H3
InChIKey
SSDVDUAQCIGPNR-UHFFFAOYSA-N
PubChem Compound ID
10847137
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [534764]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 534764J Med Chem. 1998 Dec 3;41(25):4933-8.N-n-Propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies.
Ref 534764J Med Chem. 1998 Dec 3;41(25):4933-8.N-n-Propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies.

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