Drug Information

Drug General Information
Drug ID
D0U6BT
Former ID
DNC002686
Drug Name
Rolicyclidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551388]
Formula
C16H23N
Canonical SMILES
C1CCC(CC1)(C2=CC=CC=C2)N3CCCC3
InChI
1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2
InChIKey
FYOWWXMGDATDQY-UHFFFAOYSA-N
CAS Number
CAS 2201-39-0
PubChem Compound ID
62436
PubChem Substance ID
5327729, 8188054, 14994553, 29216146, 43119553, 46507433, 50374060, 57314692, 104222398, 104325781, 127918242, 135021284, 137001268, 144205385, 160698767, 160964794, 163414450, 179323447, 198968994, 226830378, 250065469
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [551388]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 551388Leung K: 4-Acetoxy-7-chloro-3-(3-(-4-[11C]methoxybenzyl)phenyl)-2(1H)-quinolone.
Ref 551388Leung K: 4-Acetoxy-7-chloro-3-(3-(-4-[11C]methoxybenzyl)phenyl)-2(1H)-quinolone.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.