Drug Information

Drug General Information
Drug ID
D0U7OS
Former ID
DIB009006
Drug Name
CARD-024
Synonyms
1-alpha-hydroxyvitamin D5 (cardiovascular diseases), Cardiavent; 1a(OH)VitD5 (cardiovascular diseases), Cardiavent
Indication Cardiovascular disorder [ICD10:I00-I99] Phase 1 [524173]
Company
Cardiavent Inc
Target and Pathway
Target(s) Renin, renal Target Info Agonist [543623]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 524173ClinicalTrials.gov (NCT01757860) Safety and Pharmacokinetics Study of CARD-024 in Healthy Subjects. U.S. National Institutes of Health.
Ref 543623(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2413).

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