Drug Information

Drug General Information
Drug ID
D0XQ6V
Former ID
DIB016523
Drug Name
APD-515
Synonyms
ACA-1515
Indication Xerostomia [ICD9: 527.7; ICD10:K11.7, R68.2] Phase 2 [549205]
Company
Acacia Pharma Ltd
Target and Pathway
Target(s) Muscarinic receptor Target Info Agonist [550192]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Cholinergic synapse
Regulation of actin cytoskeleton
PathWhiz Pathway Muscle/Heart Contraction
Reactome Muscarinic acetylcholine receptors
Acetylcholine regulates insulin secretion
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
Regulation of Actin Cytoskeleton
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
GPCR ligand binding
GPCR downstream signaling
References
Ref 549205Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033659)
Ref 550192Clinical pipeline report, company report or official report of Acacia Pharma.

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