Drug Information

Drug General Information
Drug ID
D01KWU
Former ID
DNC001484
Drug Name
Uinagolide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535476]
Formula
C20H33N3O3S
Canonical SMILES
CCCN1CC(CC2C1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC
InChI
1S/C20H33N3O3S/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3
InChIKey
GDFGTRDCCWFXTG-UHFFFAOYSA-N
PubChem Compound ID
55645
PubChem Substance ID
17185631, 43113603, 50048636, 57313768, 78375685, 85212047, 104308123, 125823870, 126666652, 134340661, 135014614, 135830479, 144233426, 163336436, 223683727, 226973064
SuperDrug ATC ID
G02CB04
SuperDrug CAS ID
cas=087056788
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Agonist [535476]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 535476Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD. Br J Pharmacol. 2002 Jun;136(4):620-8.
Ref 535476Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD. Br J Pharmacol. 2002 Jun;136(4):620-8.

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