TTD | Drug: D0D1HS

Drug General Information
Drug ID	D0D1HS
Former ID	DNC000833
Drug Name	Ki23819
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Phase 1	[527373]
Target and Pathway
Target(s)	FL cytokine receptor	Target Info	Inhibitor	[536065]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Hematopoietic cell lineage
	Pathways in cancer
	Transcriptional misregulation in cancer
	Acute myeloid leukemia
	Central carbon metabolism in cancer
References
Ref 527373	Mol Cancer Ther. 2004 Dec;3(12):1639-49.KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth.
Ref 536065	Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase. Leukemia. 2005 Jun;19(6):930-5.

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Drug Information