Drug Information

Drug General Information
Drug ID
D0I9YI
Former ID
DIB003073
Drug Name
AZD-6942
Synonyms
CCR2b antagonists, AstraZeneca; CCR2b, AstraZeneca
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Terminated [547438]
Company
AstraZeneca plc
Target and Pathway
Target(s) C-C chemokine receptor type 2 Target Info Antagonist [550879]
KEGG Pathway Cytokine-cytokine receptor interaction
Chemokine signaling pathway
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Beta defensins
Chemokine receptors bind chemokines
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Defensins
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 547438Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016328)
Ref 550879Patent EP2727944 A1.

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