Drug Information

Drug General Information
Drug ID
D0GZ5F
Former ID
DIB009288
Drug Name
CX-1001
Synonyms
SERT ligand (cancer), Celentyx; Reprofiled marketed drug (B-cell cancers), Celentyx
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543976]
Company
Celentyx Ltd
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Binder [543976]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 543976(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 928).
Ref 543976(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 928).

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