Drug Information

Drug General Information
Drug ID
D05XGR
Drug Name
SB-214111
Synonyms
209480-37-5; SB-214111
Drug Type
Small molecular drug
Indication Unspecified Investigative [1560319]
Formula
C18H22BrN3O3S
PubChem Compound ID
6918647
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 1560319The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585.

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