Drug Information

Drug General Information
Drug ID
D03HCZ
Drug Name
Propoxyphene Hydrochloride
Synonyms
Darvon; Dolene; Kesso-gesic; Prophene 65; Propoxyphene Hydrochloride; Propoxyphene Hydrochloride 65; Darvon-n; Propoxyphene Napsylate
Drug Type
Small molecular drug
Indication Mild pain [ICD10:R52, G89] Approved [551871]
Therapeutic Class
Neurology Agents
Company
Xanodyne Pharmaceutics Inc
Formula
C22H30ClNO2
PubChem Compound ID
15329
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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