| General Information of HGF (ID: HGF0286) |
| HGF Name |
hsa-miR-10a-5p
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| HGF Synonym(s) |
microRNA 10a-5p, MIRN10a-5p, MIR10a-5p
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| Source |
Homo sapiens
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| HGF Classification |
Non-coding RNA: Micro (ncRNA-miRNA)
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| Gene Location |
chr17
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| Gene Start Site |
48579904
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Gene End Site |
48579926
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| Strand |
Reverse (-)
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| Sequence |
Click here to download the HGF sequence in FASTA format
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| External Links |
| miRBase ID |
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| Microbe Species (MIC) Regulated by This HGF |
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Bacillus thuringiensis (firmicutes)
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MIC00137
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| Description |
The miRNA hsa-miR-10a-5p plays a regulatory role in insect immunity in response to Bacillus thuringiensis. |
[1] |
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Escherichia coli (enterobacteria)
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MIC00516
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| Description |
The bone marrow-derived DC miR-10a expression was significantly downregulated by treatment with Escherichia coli and A4 bacteria (p-value<0.05). |
[2] |
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Salmonella enterica subsp. enterica (enterobacteria)
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MIC01154
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| Description |
The miR-10a-5p presents in mesenteric lymph nodes in Salmonella Typhimurium infected pigs. |
[3] |
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| References |
| 1 |
MicroRNA expression profiling of Plutella xylostella after challenge with B. thuringiensis. Dev Comp Immunol. 2019 Apr;93:115-124. doi: 10.1016/j.dci.2018.12.008. Epub 2018 Dec 22.
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| 2 |
Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. J Immunol. 2011 Dec 1;187(11):5879-86. doi: 10.4049/jimmunol.1100535. Epub 2011 Nov 7.
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| 3 |
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection. Vet Res. 2018 Feb 1;49(1):9. doi: 10.1186/s13567-018-0506-1.
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