General Information of HGF (ID: HGF1278)
HGF Name rs4986791
Source Homo sapiens
HGF Classification Single Nucleotide Polymorphism: Missense variant (SNP-MV)
Gene Location chr9:117713324
SNP in Gene
TLR4
Microbe Species (MIC) Regulated by This HGF
         Cutibacterium acnes (actinobacteria) MIC01031
             Description The rs4986791 SNP is significantly associated with the abundance of Propionibacterium acnes (p-value<0.05). [1]
         Escherichia coli (enterobacteria) MIC00516
             Description The TLR4 rs4986791 SNP is significantly associated with Escherichia coli colonization in the first month of life. [2]
References
1 Single nucleotide polymorphisms of toll-like receptor-4 protect against acne conglobata.J Eur Acad Dermatol Venereol. 2012 Dec;26(12):1538-43. doi: 10.1111/j.1468-3083.2011.04338.x. Epub 2011 Nov 16.
2 Host-microbial interactions in childhood atopy: toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coli.J Allergy Clin Immunol. 2010 Jan;125(1):231-6.e1-5. doi: 10.1016/j.jaci.2009.10.011.

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